BDBM737453 US20250136618, Compound 9

SMILES [2H]C([2H])([2H])N1C(=O)CNc2ccc(OCCNC[C@H]3CN(c4cnc5c(n4)NC(=O)CS5)C(=O)O3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737453   

TargetDNA topoisomerase 4 subunit A/B(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737453(US20250136618, Compound 9)
Affinity DataIC50: 91nMAssay Description:E. coli topoisomerase IV decatenation activity and its inhibition was assayed using a kit procured from Inpiralis (D4002) and the kit protocol was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Bugworks Research India

US Patent
LigandPNGBDBM737453(US20250136618, Compound 9)
Affinity DataIC50: 170nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent