BDBM737481 US20250136619, Compound I-77

SMILES CCc1cnn2c(CCc3ccc(CCOCCOCCOCCOCCN(C)C/C=C/C(=O)N(C)CCOc4c(N)ncnc4-c4cc(F)cc(CC(=O)c5ccc(C6CC6)cc5F)c4C)nc3)cc(N3CCCC[C@H]3CCO)nc12

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737481   

TargetCyclin-dependent kinase 9(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737481(US20250136619, Compound I-77)
Affinity DataKd:  275nMAssay Description:Binding reactions were assembled by combining kinases, liganded affinity beads, and test compounds in 1×binding buffer (20% SeaBlock, 0.17×PBS, 0.05%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Halda Therapeutics OPCO

US Patent
LigandPNGBDBM737481(US20250136619, Compound I-77)
Affinity DataKd:  1.50E+3nMAssay Description:Compounds were tested using a KdELECT assay. Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent