BDBM742453 4-[7-[[2-cyano- 4-methyl-1-[[3- (sulfamoylamino)-1- bicyclo[1.1.1] pentanyl] methyl]indol-5- yl]methyl]- 2,7-diazaspiro [3.5]nonan-2-yl]-6- (2,2,2-trifluoroethyl) quinazoline Example 62::US20250163061, Compound 61

SMILES Cc1c(CN2CCC3(CC2)CN(c2ncnc4ccc(CC(F)(F)F)cc24)C3)ccc2c1cc(C#N)n2CC12CC(NS(N)(=O)=O)(C1)C2

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742453   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742453(4-[7-[[2-cyano- 4-methyl-1-[[3- (sulfamoylamino)-1...)
Affinity DataEC50: <75nMAssay Description:Compound activity was determined using recombinant MEN1 protein (Creativebiomart, Cat #MEN1-35H) and a custom fluorescein-labeled MLL4-43 peptide (Et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent