BDBM74865 (E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-thiophen-2-yl-2-thiazolyl)-2-propenamide::(E)-2-cyano-3-[5-(4-fluorophenyl)-2-furyl]-N-[4-(2-thienyl)thiazol-2-yl]acrylamide::(E)-2-cyano-3-[5-(4-fluorophenyl)furan-2-yl]-N-(4-thiophen-2-yl-1,3-thiazol-2-yl)prop-2-enamide::MLS000402434::SMR000262229::cid_2328888

SMILES Fc1ccc(cc1)-c1ccc(\C=C(/C#N)C(=O)Nc2nc(cs2)-c2cccs2)o1

InChI Key InChIKey=ULZPTBQRPJKARJ-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 74865   

TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50:  2.72E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetDelta-type opioid receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50: >6.46E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetTropomyosin alpha-1 chain(Pig)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50: >7.15E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetMelanocortin receptor 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50: >8.92E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetEndoribonuclease toxin MazF(Escherichia coli (strain K12))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM74865((E)-2-cyano-3-[5-(4-fluorophenyl)-2-furanyl]-N-(4-...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay