BDBM7505 2,6,9-Trisubstituted purine deriv. 5a::2-iodo-N,9-dimethyl-N-(prop-2-en-1-yl)-9H-purin-6-amine::CHEMBL336117

SMILES CN(CC=C)c1nc(I)nc2n(C)cnc12

InChI Key InChIKey=ASHNQGPAOFGMPH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7505   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Institut Curie

LigandPNGBDBM7505(2-iodo-N,9-dimethyl-N-(prop-2-en-1-yl)-9H-purin-6-...)
Affinity DataIC50: 1.80E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM7505(2-iodo-N,9-dimethyl-N-(prop-2-en-1-yl)-9H-purin-6-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1 (CDK1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM7505(2-iodo-N,9-dimethyl-N-(prop-2-en-1-yl)-9H-purin-6-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was tested for its inhibitory activity against cyclin-dependent kinase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Institut Curie

LigandPNGBDBM7505(2-iodo-N,9-dimethyl-N-(prop-2-en-1-yl)-9H-purin-6-...)
Affinity DataIC50: 4.00E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed