BDBM753614 Preparation of 6-((2-acetyl-2-azaspiro[3.3]heptan-6-yl)amino)-2-isopropoxypyrimidine-4-carboxylic acid (for example this intermediate could be used as an intermediate for the compound of Example 200)::US20250206717, Example 20

SMILES O=C(c1cc(NC2CCN(C(=O)C3CCC3)CC2)nc(-c2ccccc2)n1)N1CC[C@@H](N2CCc3ccccc3C2)[C@H](O)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753614   

TargetProtein arginine N-methyltransferase 5(Human)
Innovstone Therapeutics

US Patent
LigandPNGBDBM753614(Preparation of 6-((2-acetyl-2-azaspiro[3.3]heptan-...)
Affinity DataIC50: 20nMAssay Description:A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100ML), and 1 mM DTT (Sigma, Cat. No. D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
10/20/2025
Entry Details
US Patent