BDBM753622 Preparation of 6-((1-(cyclobutanecarbonyl)piperidine-4-yl)amino)-2-(pyrrolidin-1-yl)pyrimidine-4-carboxylic acid (for example this intermediate could be used as an intermediate for the compound of Example 304)::US20250206717, Example 28

SMILES CC(=O)N1CCC(Nc2cc(C(=O)N3CC[C@@H](N4CCc5ccccc5C4)[C@H](O)C3)nc(-c3cccc(F)c3)n2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753622   

TargetProtein arginine N-methyltransferase 5(Human)
Innovstone Therapeutics

US Patent
LigandPNGBDBM753622(Preparation of 6-((1-(cyclobutanecarbonyl)piperidi...)
Affinity DataIC50: 20nMAssay Description:A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100ML), and 1 mM DTT (Sigma, Cat. No. D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent