BDBM753627 Preparation of 6-((1-acetylpiperidine-4-yl)amino)-2-cyclohexylpyrimidine-4-carboxylic acid (for example this intermediate could be used as an intermediate for the compound of Example 357)::US20250206717, Example 33

SMILES CC(=O)N1CC2(CC(Nc3cc(C(=O)N4CC[C@@H](N5CCc6ccccc6C5)[C@H](O)C4)nc(-c4cncs4)n3)C2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 753627   

TargetProtein arginine N-methyltransferase 5(Human)
Innovstone Therapeutics

US Patent
LigandPNGBDBM753627(Preparation of 6-((1-acetylpiperidine-4-yl)amino)-...)
Affinity DataIC50: 20nMAssay Description:A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100ML), and 1 mM DTT (Sigma, Cat. No. D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/20/2025
Entry Details
US Patent