BDBM761313 CHEM-US-00323 4-(8-((5-methoxy-7-methyl-1H-indol-4- yl)methyl)-2-oxa-8-azaspiro[4.5]decan- 7-yl)benzoic acid::US20250243186, Example 36

SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC2(CCOC2)CC1c1ccc(C(=O)O)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761313   

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761313(CHEM-US-00323 4-(8-((5-methoxy-7-methyl-1H-indol-4...)
Affinity DataIC50: 16.6nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761313(CHEM-US-00323 4-(8-((5-methoxy-7-methyl-1H-indol-4...)
Affinity DataIC50: 125nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent