BDBM761325 US20250243186, Example 47

SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC2(CC1c1ccc(-c3noc(=O)[nH]3)cc1)CC(F)(F)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761325   

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761325(US20250243186, Example 47)
Affinity DataKd:  0.530nMAssay Description:Table 2: Biacore 8 k instrument was primed using 1× PBS-P+ buffer before docking a Cytiva NTA chip. Recombinant human Factor B catalytic domain were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetComplement factor B [470-764](Human)
Hansoh Bio

US Patent
LigandPNGBDBM761325(US20250243186, Example 47)
Affinity DataIC50: 2nMAssay Description:Table 1: Factor B binding affinity of each compound tested was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent