BDBM76395 (E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one::(E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one::MLS000438984::SMR000113000::cid_5331295

SMILES COc1ccc(\C=C\C(=O)c2ccccc2O)cc1

InChI Key InChIKey=NXBNYUSXDBHELA-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 76395   

TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 1.06E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 6(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 6.00E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetCaspase-3(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 2.31E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetAcetylcholinesterase(Pacific electric ray)
Quaid-I-Azam University

LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 9.29E+4nMpH: 8.0 T: 2°CAssay Description:In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2012
Entry Details Article
PubMed
TargetATP-diphosphohydrolase 1(Blood fluke)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of Schistosoma mansoni ATPDase1 incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI cells using kynuramine as substrate incubated for 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI cells using kynuramine as substrate incubated for 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetShiga toxin subunit A(Shigella dysenteriae)
TBA

Curated by ChEMBL
LigandPNGBDBM76395((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...)
Affinity DataKi:  9.93E+3nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit assessed as change in transition temperature by SYPRO orange dye based fluorescence-b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMed