BDBM764648 N-[[1-[(4-propan-2-yloxypiperidin-1-yl)methyl]cyclobutyl]::US20250257057, Example 51

SMILES CC(C)OC1CCN(CC2(CNC(=O)c3cc4c(s3)CCCCCC4)CCC2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 764648   

TargetCX3C chemokine receptor 1(Mouse)
University of Texas System

US Patent
LigandPNGBDBM764648(N-[[1-[(4-propan-2-yloxypiperidin-1-yl)methyl]cycl...)
Affinity DataEC50:  15.4nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetCX3C chemokine receptor 1(Human)
University of Texas System

US Patent
LigandPNGBDBM764648(N-[[1-[(4-propan-2-yloxypiperidin-1-yl)methyl]cycl...)
Affinity DataEC50:  15.7nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetCX3C chemokine receptor 1(Rat)
University of Texas System

US Patent
LigandPNGBDBM764648(N-[[1-[(4-propan-2-yloxypiperidin-1-yl)methyl]cycl...)
Affinity DataEC50:  34.8nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent