BDBM766909 (S)—N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl)-6-isopropoxy-2-((tetrahydrofuran-3-yl)methyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide and (R)—N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl)-6-isopropoxy-2-((tetrahydrofuran-3-yl)methyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide::US20250268877, Example 5

SMILES CC(C)Oc1nc2nn(C[C@H]3CCOC3)cc2cc1C(=O)Nc1cccn(C2CC2)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766909   

LigandPNGBDBM766909((S)—N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl...)
Affinity DataIC50: 200nMAssay Description:IRAK4 protein. N-terminal His-TEV-AVI tagged catalytical domain of human IRAK4 (a.a. 163-460) was co-expressed with Bir A in insect cells, and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/8/2025
Entry Details
US Patent