BDBM7701 2-Oxo-3-(4-sulfamoyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-4-carboxylic acid ethyl ester::Oxindole-Based Inhibitor 37::ethyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]methylidene}-2,3-dihydro-1H-indole-4-carboxylate

SMILES CCOC(=O)c1cccc2NC(=O)C(C=Nc3ccc(cc3)S(N)(=O)=O)c12

InChI Key InChIKey=CEMOAZMENLYUBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7701   

TargetCyclin-dependent kinase 2(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7701(ethyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]meth...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7701(ethyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]meth...)
Affinity DataIC50: 8.90nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
LigandPNGBDBM7701(ethyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]meth...)
Affinity DataIC50: 130nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7701(ethyl (3Z)-2-oxo-3-{[(4-sulfamoylphenyl)amino]meth...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed