BDBM770153 23-[(3-fluoro-2-methoxyphenyl)amino]-8,11- dioxa-5,18,22- triazatetracyclo[18.2.1.02,7.016,21]tricosa- 1(23),2,4,6,20-pentaen-19-one::US20250282795, Compound 100

SMILES COc1c(F)cccc1Nc1c2[nH]c3c1C(=O)NCC3CCCCOCCOc1cnccc1-2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770153   

TargetEpidermal growth factor receptor(Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770153(23-[(3-fluoro-2-methoxyphenyl)amino]-8,11- dioxa-5...)
Affinity DataEC50: <1nMAssay Description:Table D: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210,T790M](Human)
Celyn Therapeutics

US Patent
LigandPNGBDBM770153(23-[(3-fluoro-2-methoxyphenyl)amino]-8,11- dioxa-5...)
Affinity DataEC50:  3nMAssay Description:Table B: The enzymatic assay used to determine activity was a Luminescence assay using a Microplate Reader ClarioStar Plus. The enzymatic reaction wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent