BDBM771614 US20250092044, Comparative Example A

SMILES COc1nn(C)cc1-c1[nH]c2ncc3c(c2c1-c1ccc2c(cnn2C)c1)n(C1CCOCC1)c(=O)n3C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 771614   

LigandPNGBDBM771614(US20250092044, Comparative Example A)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte

US Patent
LigandPNGBDBM771614(US20250092044, Comparative Example A)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandPNGBDBM771614(US20250092044, Comparative Example A)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM771614(US20250092044, Comparative Example A)
Affinity DataIC50: 1.88E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent