BDBM771850 13-chloro-19,21-difluoro-14-hydroxy-10,16,16-trioxo-9-oxa-16λ6-thia-17-azatetracyclo[16.3.1.111,15.02,7]tricosa-1(21),2(7),3,5,11,13,15(23),18(22),19-nonaene-5-carbonitrile ::US20250289793, Compound 85

SMILES N#Cc1ccc2c(c1)COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc-2c(F)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771850   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771850(13-chloro-19,21-difluoro-14-hydroxy-10,16,16-triox...)
Affinity DataIC50: 20nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent