BDBM774735 (E)-3-(4-(((1-(3- Cyano-4-(4-cyano-3- fluorophenyl)-5-(3- hydroxy-4-methoxy- phenyl)pyridin- 2-yl)piperidin-4- yl)(methyl)amino) methyl)phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 42

SMILES COc1ccc(-c2cnc(N3CCC(N(C)Cc4ccc(/C=C/C(=O)NO)cc4)CC3)c(C#N)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774735   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774735((E)-3-(4-(((1-(3- Cyano-4-(4-cyano-3- fluorophenyl...)
Affinity DataIC50: 0.330nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774735((E)-3-(4-(((1-(3- Cyano-4-(4-cyano-3- fluorophenyl...)
Affinity DataIC50: 7.33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774735((E)-3-(4-(((1-(3- Cyano-4-(4-cyano-3- fluorophenyl...)
Affinity DataIC50: 9.25nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774735((E)-3-(4-(((1-(3- Cyano-4-(4-cyano-3- fluorophenyl...)
Affinity DataIC50: 328nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent