BDBM774763 (E)-3-(4-(((1-(4-(4-cyano-3-fluorophenyl)-5-(3-hydroxy-4-methoxyphenyl)-3-methoxypyridin-2-yl)piperidin-4-yl)amino)methyl)phenyl)-N-hydroxyacrylamide::US20250304549, Example 88

SMILES COc5ccc(c3cnc(N2CCC(NCc1ccc(/C=C/C(=O)NO)cc1)CC2)c(OC)c3c4ccc(C#N)c(F)c4)cc5O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774763   

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774763((E)-3-(4-(((1-(4-(4-cyano-3-fluorophenyl)-5-(3-hyd...)
Affinity DataIC50: 0.210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774763((E)-3-(4-(((1-(4-(4-cyano-3-fluorophenyl)-5-(3-hyd...)
Affinity DataIC50: 5.09nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774763((E)-3-(4-(((1-(4-(4-cyano-3-fluorophenyl)-5-(3-hyd...)
Affinity DataIC50: 28.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774763((E)-3-(4-(((1-(4-(4-cyano-3-fluorophenyl)-5-(3-hyd...)
Affinity DataIC50: 178nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent