BDBM774815 (E)-3-(4-(((1-(4- (4-Cyano-3- fluorophenyl)-5- (3-hydroxy-4- methoxyphenyl)- 3-methylpyridin- 2-yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide hydrochloride::US20250304549, Example 144

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c(C)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774815   

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774815((E)-3-(4-(((1-(4- (4-Cyano-3- fluorophenyl)-5- (3-...)
Affinity DataIC50: 0.210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774815((E)-3-(4-(((1-(4- (4-Cyano-3- fluorophenyl)-5- (3-...)
Affinity DataIC50: 0.860nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774815((E)-3-(4-(((1-(4- (4-Cyano-3- fluorophenyl)-5- (3-...)
Affinity DataIC50: 1.07nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandPNGBDBM774815((E)-3-(4-(((1-(4- (4-Cyano-3- fluorophenyl)-5- (3-...)
Affinity DataIC50: 91.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent