BDBM775119 US12435062, Compound 45

SMILES Cn1cc(Nc2cc(Oc3ccc(NC(=O)c4cnc5n(c4=O)CCC5)nc3)ccn2)cn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775119   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandChemical structure of BindingDB Monomer ID 775119BDBM775119(US12435062, Compound 45)
Affinity DataIC50: 0.00900nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent