BDBM77575 4-chlorobenzoic acid [[amino-(5-nitro-2-thiazolyl)methylidene]amino] ester::4-chlorobenzoic acid [[amino-(5-nitrothiazol-2-yl)methylene]amino] ester::MLS000859515::O2-(4-chlorobenzoyl)-5-nitro-1,3-thiazole-2-carbohydroximamide::SMR000461292::[[amino-(5-nitro-1,3-thiazol-2-yl)methylidene]amino] 4-chlorobenzoate::[[azanyl-(5-nitro-1,3-thiazol-2-yl)methylidene]amino] 4-chloranylbenzoate::cid_2743681

SMILES CCc1cc(O)c(F)cc1-c1ccc2c(-c3nc4c([nH]3)CN(C3CCCN3C(=O)N3CCCC3N3Cc5nc(-c6n[nH]c7cc(-c8cc(F)c(O)cc8CC)ccc67)[nH]c5C3)C4)n[nH]c2c1

InChI Key InChIKey=DWTASHGCZIDBGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 77575   

TargetNT-3 growth factor receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77575BDBM77575((2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazo...)
Affinity DataIC50: 1.49nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77575BDBM77575((2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazo...)
Affinity DataIC50: 2.82nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77575BDBM77575((2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazo...)
Affinity DataIC50: 5.86nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent