BDBM7759 N-(1,2-dihydroisoquinolin-2-yl)-4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8-tetraen-12-ylidene]methyl}amino)benzene-1-sulfonamide::Oxindole-Based Inhibitor 95

SMILES O=C1Nc2ccc3ncsc3c2C1C=Nc1ccc(cc1)S(=O)(=O)NN1Cc2ccccc2C=C1

InChI Key InChIKey=WCBSYOIQJMDBSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7759   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7759(N-(1,2-dihydroisoquinolin-2-yl)-4-({[(12Z)-11-oxo-...)
Affinity DataIC50: 9.5nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
LigandPNGBDBM7759(N-(1,2-dihydroisoquinolin-2-yl)-4-({[(12Z)-11-oxo-...)
Affinity DataIC50: 42nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed