BDBM777374 US12441708, Example 28::US20250313547, Example 28

SMILES Cc1c(-n2ccc(=O)[nH]c2=O)cnc2ccccc12

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 777374   

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777374(US20250313547, Example 28 | US12441708, Example 28)
Affinity DataKd:  5.50E+4nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777374(US20250313547, Example 28 | US12441708, Example 28)
Affinity DataKd:  5.50E+4nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/4/2026
Entry Details
US Patent