BDBM778107 US20250313560, Example trans-E53a

SMILES C[C@@H](NC(=O)c1cc(N2CCC(NC3CCC[C@@]3(C)O)CC2)c2ncnn2c1)c1cccc(C(F)(F)F)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 778107   

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778107(US20250313560, Example trans-E53a)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778107(US20250313560, Example trans-E53a)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778107(US20250313560, Example trans-E53a)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent