BDBM778117 US20250313560, Example E62

SMILES C[C@@H]1C[C@@H](O)CN1[C@H]1CC[C@H](c2cc(C(=O)N[C@H](C)c3cccc(C(F)F)c3F)cn3ncnc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 778117   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778117(US20250313560, Example E62)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778117(US20250313560, Example E62)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778117(US20250313560, Example E62)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent