BDBM778138 US20250313560, Example E81

SMILES C[C@@H](NC(=O)c1cc([C@H]2CC[C@H](N3CCC[C@H](O)C3)CC2)c2nncn2c1)c1cccc(C(F)F)c1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 778138   

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778138(US20250313560, Example E81)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778138(US20250313560, Example E81)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM778138(US20250313560, Example E81)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent