BDBM7794 2,4-diethyl-3-sulfanylidene-1,2,4-thiadiazolidin-5-one::2,4-diethyl-3-thioxo-1,2,4-thiadiazolidin-5-one::Thiadiazolidinone (TDZD) deriv. 21

SMILES CCn1sc(=O)n(CC)c1=S

InChI Key InChIKey=LDHHNMNHSWWSNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7794   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7794(2,4-diethyl-3-thioxo-1,2,4-thiadiazolidin-5-one | ...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7794(2,4-diethyl-3-thioxo-1,2,4-thiadiazolidin-5-one | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed