BDBM779946 US12440481, Compound 2::methyl 4-[[3-cyclopropyl-6-[2-methoxy-4-(trifluoromethoxy)phenoxy]-2-methyl-benzoyl]amino]-5-methyl-pyridine-2-carboxylate

SMILES COC(=O)c1cc(NC(=O)c2c(Oc3ccc(OC(F)(F)F)cc3OC)ccc(C3CC3)c2C)c(C)cn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 779946   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM779946(methyl 4-[[3-cyclopropyl-6-[2-methoxy-4-(trifluoro...)
Affinity DataIC50: 300nMAssay Description:1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropylene compound plates at 250× d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent