BDBM779977 US12440481, Compound 35

SMILES COC(=O)c1cc(NC(=O)c2c(Oc3ccc(OC(F)(F)F)c(F)c3OC)ccc(C(F)(F)F)c2F)cc(C(=O)OC)n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 779977   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM779977(US12440481, Compound 35)
Affinity DataIC50: 300nMAssay Description:1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropylene compound plates at 250× d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent