BDBM780226 N-(3-(1,1-difluoroethyl)phenyl)-1-(4-(difluoromethoxy)-3-(pyridin-3-yl)phenyl)-3,5-::US12441689, Compound 179

SMILES Cc3nn(c2ccc(OC(F)F)c(c1cccnc1)c2)c(C)c3C(=O)Nc4cccc(C(C)(F)F)c4

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780226   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Epivario

US Patent
LigandChemical structure of BindingDB Monomer ID 780226BDBM780226(N-(3-(1,1-difluoroethyl)phenyl)-1-(4-(difluorometh...)
Affinity DataIC50: 55nMAssay Description:10 nM of human ACSS2 protein (OriGene Technologies, Inc) was incubated for 90 minutes at 37 C with various compounds' concentrations in a reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent