BDBM780304 N-(2,4-dimethoxybenzyl)-2-(methylthio)- 4-morpholinopyrimidine-5-carboxamide::US12441690, Example 9

SMILES COc1ccc(CNC(=O)c2cnc(SC)nc2N2CCOCC2)c(OC)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780304   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University R&D Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 780304BDBM780304(N-(2,4-dimethoxybenzyl)-2-(methylthio)- 4-morpholi...)
Affinity DataIC50: 377nMAssay Description:In order to evaluate the PDE4B inhibitory activity of the compounds according to the present invention, the following experiment was performed using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent