BDBM780315 N-(4-amino-3,5-diisopropylphenyl)-4- (3,4-dimethoxyphenyl)-2- (trifluoromethyl)pyrimidine-5- carboxamide::US12441690, Example 21

SMILES COc1ccc(-c2nc(C(F)(F)F)ncc2C(=O)Nc2cc(C(C)C)c(N)c(C(C)C)c2)cc1OC

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780315   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University R&D Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 780315BDBM780315(N-(4-amino-3,5-diisopropylphenyl)-4- (3,4-dimethox...)
Affinity DataIC50: 222nMAssay Description:In order to evaluate the PDE4B inhibitory activity of the compounds according to the present invention, the following experiment was performed using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent