BDBM780318 N-(2-(1H-indole-3-yl)ethyl)-4- morpholino-2- (trifluoromethyl)pyrimidine-5- carboxamide::US12441690, Example 24

SMILES O=C(NCCc1c[nH]c2ccccc12)c1cnc(C(F)(F)F)nc1N1CCOCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780318   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University R&D Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 780318BDBM780318(N-(2-(1H-indole-3-yl)ethyl)-4- morpholino-2- (trif...)
Affinity DataIC50: 469nMAssay Description:In order to evaluate the PDE4B inhibitory activity of the compounds according to the present invention, the following experiment was performed using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent