BDBM781620 3-(5-(4-benzhydryl-3,5- dimethylpiperazine-1- carbonyl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250320193, Compound GT-06059

SMILES CC1CN(C(=O)c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC(C)N1C(c1ccccc1)c1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 781620   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 781620BDBM781620(3-(5-(4-benzhydryl-3,5- dimethylpiperazine-1- carb...)
Affinity DataIC50: 500nMAssay Description:The CEREBLON BINDING kits (specification: 10,000 tests; product number: Catalog #64BDCRBNPEH; CISBIO company) was used to determine the CRBN binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent