BDBM781622 3-(5-(((R)-4-benzhydryl-2- methylpiperazin-1- yl)methyl)-7-fluoro-1- oxoisoindolin-2- yl)piperidine-2,6-dione::US20250320193, Compound GT-03577

SMILES C[C@@H]1CN(C(c2ccccc2)c2ccccc2)CCN1Cc1cc(F)c2c(c1)CN(C1CCC(=O)NC1=O)C2=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 781622   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 781622BDBM781622(3-(5-(((R)-4-benzhydryl-2- methylpiperazin-1- yl)m...)
Affinity DataIC50: 500nMAssay Description:The CEREBLON BINDING kits (specification: 10,000 tests; product number: Catalog #64BDCRBNPEH; CISBIO company) was used to determine the CRBN binding ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/5/2026
Entry Details
US Patent