BDBM782046 US12447153, Example 103

SMILES C=CC(=O)N1CCN(c2ccc3ncnc(Nc4ccc(Oc5ccc6c(c5)ncn6C)c(C)c4)c3n2)CC1(C)C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782046   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 782046BDBM782046(US12447153, Example 103)
Affinity DataIC50: 2.90nMAssay Description:Compound potencies were determined using CisBio's HTRF Kinease-TK assay technology. The kinases were incubated with 250 nM TK-substrate biotin (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/9/2026
Entry Details
US Patent