BDBM782288 US12447153, Example 345

SMILES C=CC(=O)N1CCN(c2ccc3ncnc(Nc4cc(Cl)c(Oc5ccn6ncnc6c5)cc4F)c3n2)C[C@H]1COC

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782288   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 782288BDBM782288(US12447153, Example 345)
Affinity DataIC50: 9.40nMAssay Description:Compound potencies were determined using CisBio's HTRF Kinease-TK assay technology. The kinases were incubated with 250 nM TK-substrate biotin (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/9/2026
Entry Details
US Patent