BDBM783070 N-(6,6-Dimethyltetrahydro-2H-pyran-3-yl)-6-(1H-imidazol-1-yl)-4-methylpicolinamide::US20250326739, Compound 29A

SMILES Cc1cc(C(=O)NC2CCC(C)(C)OC2)nc(-n2ccnc2)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 783070   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM783070(N-(6,6-Dimethyltetrahydro-2H-pyran-3-yl)-6-(1H-imi...)
Affinity DataIC50: 5.5nMAssay Description:Required reaction buffer, required CD38 concentration in reaction buffer and required e-NAD concentration in reaction buffer were prepared. Thereafte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM783070(N-(6,6-Dimethyltetrahydro-2H-pyran-3-yl)-6-(1H-imi...)
Affinity DataIC50: 65nMAssay Description:Required reaction buffer, required CD38 concentration in reaction buffer and required e-NAD concentration in reaction buffer were prepared. Thereafte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent