BDBM783127 N-(4-((7-morpholinoimidazo[1,2-c]pyrimidin-5-yl)oxy)cyclohexyl)pyrazin-2-amine::US20250326754, Compound 3

SMILES c1cnc(NC2CCC(Oc3nc(N4CCOCC4)cc4nccn34)CC2)cn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783127   

TargetDNA-dependent protein kinase catalytic subunit(Human)
adMare Therapeutics Society

US Patent
LigandChemical structure of BindingDB Monomer ID 783127BDBM783127(N-(4-((7-morpholinoimidazo[1,2-c]pyrimidin-5-yl)ox...)
Affinity DataIC50: 0.75nMAssay Description:A biochemical assay was performed to identify IC50 values against DNA-PK activity in a two-step reaction with a kinase reaction followed by ADP Glo™ ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent