BDBM783728 US20250333404, Compound 1

SMILES Cc2cc(S(=O)(=O)Nc1cscn1)c(F)cc2N(C)[C@H]4CCN(Cc3ccccc3)C4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 783728   

TargetSodium channel protein type 8 subunit alpha(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM783728(US20250333404, Compound 1)
Affinity DataIC50: 272nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM783728(US20250333404, Compound 1)
Affinity DataIC50: 1.56E+4nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM783728(US20250333404, Compound 1)
Affinity DataIC50: 2.43E+4nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details US Patent