BDBM783826 (4S)-8-[3-(3,4-dichloro-2- methyl- 2H-indazol-5-yl)-5-methyl- 1H-pyrazolo[3,4-b] pyrazin-6-yl]-2- oxa-8-azaspiro[4.5] decan-4-amine::US12458640, Example 4

SMILES Cc1nc2c(-c3ccc4nn(C)c(Cl)c4c3Cl)n[nH]c2nc1N1CCC2(CC1)COC[C@H]2N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783826   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 783826BDBM783826((4S)-8-[3-(3,4-dichloro-2- methyl- 2H-indazol-5-yl...)
Affinity DataIC50: 5.30nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent