BDBM783910 (1R)-8-[3-(3,4-dichloro-2- methyl-2H-indazol-5-yl)- 5-methyl-1H- pyrazolo[3,4-b]pyrazin- 6-yl]-8-azaspiro[4.5]decan- 1-amine::US12458640, Example 15

SMILES Cc1nc2c(-c3ccc4nn(C)c(Cl)c4c3Cl)n[nH]c2nc1N1CCC2(CCC[C@H]2N)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783910   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 783910BDBM783910((1R)-8-[3-(3,4-dichloro-2- methyl-2H-indazol-5-yl)...)
Affinity DataIC50: 7.60nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent