BDBM783912 {6-[(3S,4S)-4-amino-3- methyl-2- oxa-8-azaspiro[4.5] decan-8-yl]- 3-[5-chloro-3- (dimethylamino) quinoxalin-6-yl]-1H- pyrazolo[3,4-b]pyrazin- 5-yl}methanol::US12458640, Example 17

SMILES C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccc6ncc(N(C)C)nc6c5Cl)c4nc3CO)CC2)[C@@H]1N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783912   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 783912BDBM783912({6-[(3S,4S)-4-amino-3- methyl-2- oxa-8-azaspiro[4....)
Affinity DataIC50: 14nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent