BDBM784317 US20250340529, Compound 449

SMILES O=C1CC[C@@H](CNCCN2C(=O)COc3cc(-c4cccc(-c5cccc(-c6ccc7c(c6)OCC(=O)N7CCNC[C@@H]6CCC(=O)N6)c5Cl)c4Cl)ccc32)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784317   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Ascletis Bioscience Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 784317BDBM784317(US20250340529, Compound 449)
Affinity DataIC50: 3.89nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent