BDBM784655 5-[4-(3,3-Difluoro-4,4-dimethyl-pyrrolidin-1-yl)pyrazolo[3,4-d]pyrimidin-2-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 13

SMILES CC1(C)CN(c2ncnc3nn(-c4c[nH]c(=O)[nH]c4=O)cc23)CC1(F)F

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784655   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784655(5-[4-(3,3-Difluoro-4,4-dimethyl-pyrrolidin-1-yl)py...)
Affinity DataIC50: 44.8nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent