BDBM784720 D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Leu-Yme-Nal-Aib-Asp(@1)-Asn-Asn-NH2|SCXXXXXXXXXZXX::WO2025051920, Example 1

SMILES COc1ccc(C[C@@H]2NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)C([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](NC(C)=O)CCCCNC(=O)C[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](Cc3ccc4ccccc4c3)NC2=O)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784720   

TargetInterleukin-23 subunit alpha/receptor(Human)
Sanofi-Aventis Deutschland

WIPO
LigandPNGBDBM784720(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Leu-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 0.630nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Target InfoPDB
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Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025051920