BDBM784761 D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Cit-Asp(@1)-Asn-Asn-NH2|SCXXXXXXXXXZXX::WO2025051920, Example 29

SMILES COc1ccc(C[C@@H]2NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)C([C@@H](C)O)NC(=O)[C@H](CC(N)=O)NC(=O)C(NC(C)=O)CCCCNC(=O)C[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O)NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](Cc3ccc4ccccc4c3)NC2=O)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784761   

TargetInterleukin-23 subunit alpha/receptor(Human)
Sanofi-Aventis Deutschland

WIPO
LigandPNGBDBM784761(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Cit-Asp(...)
Affinity DataIC50: 5.63nMAssay Description:A 384-well plate was coated with 50 pl/well of human IL-23 at a final concentration of 1 pg/ml and incubated overnight at 4°C. The wells were washed ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025051920