BDBM785079 US12466818, Compound 1.033::US20250387379, Compound 4.033

SMILES NCCONC(=O)c1c(Nc2ccc(I)cc2F)sc2c1CCCC2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 785079   

TargetMitogen-activated protein kinase kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 785079BDBM785079(US12466818, Compound 1.033 | US20250387379, Compou...)
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/2/2026
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 1(Human)
Nflection Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 785079BDBM785079(US12466818, Compound 1.033 | US20250387379, Compou...)
Affinity DataIC50: 150nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent