BDBM785399 US20250346564, Example 23

SMILES CC1(NS(=O)(=O)c2ccc3cnn(-c4nnc(C(F)F)s4)c3c2)COC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 785399   

TargetPoly(ADP-ribose) glycohydrolase(Human)
ARase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 785399BDBM785399(US20250346564, Example 23)
Affinity DataIC50: 275nMAssay Description:The ability of the compounds of the Examples to inhibit PARG activity in 4. (trifluoromethyl)umbelliferone (TFMU) assay was determined as described b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details
US Patent